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sexual health

PrEP, PEP, DoxyPEP, U=U, testing and chemsex harm reduction for gay, bi and queer men

Looking after your sexual health is part of playing well. The tools available now are better than they have ever been: HIV can be prevented with a pill or an injection, people living with HIV on effective treatment don't pass it on through sex, and many bacterial STIs can be prevented after the fact. This page covers what each tool does and how often to get tested.

This page is general information, not medical advice. Medicines, doses and recommendations vary by country and change over time, so talk to a sexual health clinic or a doctor before starting or stopping anything. See our legal policies.

Had sex that might have exposed you to HIV in the last 72 hours?

Ask for PEP now, at a sexual health clinic, an emergency department or an urgent care service. It works best the sooner you start, ideally within hours, and it isn't given after 72 hours. Our support & crisis lines page lists where to get it.

prep

Pre-exposure prophylaxis is HIV medicine taken by people who don't have HIV, to stop them getting it. Taken as prescribed, it is highly effective at preventing HIV through sex.

daily pills

One pill every day. It's the most widely available option, and it suits people whose sex isn't predictable.

on demand

Also called event-based or 2-1-1 dosing: pills taken before and after sex on a set schedule. It's recommended for cis men having anal sex, not for everyone, and it isn't suitable for people with hepatitis B. Ask your clinic before switching to it.

injections

Long-acting injections given every couple of months, or twice a year in some countries. They're good if remembering pills is hard.

what it involves

An HIV test before you start and regular check-ups while you're on it, usually every three months, with STI and kidney tests.

PrEP doesn't protect against syphilis, gonorrhoea, chlamydia or mpox. Pair it with testing, and with condoms or DoxyPEP where they fit.

pep

Post-exposure prophylaxis is a course of HIV medicine started after a possible exposure, such as a condom breaking, condomless sex with someone whose status you don't know, or a sexual assault. You take it for 28 days.

doxypep

Doxycycline post-exposure prophylaxis is a single dose of a common antibiotic taken within 72 hours after condomless sex. It greatly lowers the chance of getting syphilis and chlamydia, and it helps less against gonorrhoea.

u=u

Undetectable = Untransmittable. A person living with HIV who takes treatment and keeps an undetectable viral load does not pass HIV on through sex. This is backed by large studies of thousands of couples, and by every major health body.

Disclosure laws differ by country. In some places, not telling a partner about HIV can still be a crime even with an undetectable viral load, so check the law where you live. Knowing about U=U helps fight stigma, and many people living with HIV find it changes how they date and play.

condoms & lube

testing

Many STIs have no symptoms, so regular testing is the only way to know. A common guide for sexually active gay and bi men:

If you…Test for HIV, syphilis, gonorrhoea and chlamydia
have one regular partnerat least once a year
have several or new partners, or anonymous playevery 3 to 6 months
take PrEPevery 3 months, at your PrEP check-up
have symptoms, or a partner tells you they've tested positivenow, whatever your last test was

vaccines

Ask your clinic about vaccines for hepatitis A and B, HPV (which protects against genital warts and some cancers, often offered free to gay and bi men up to a certain age), and mpox. Some places also offer meningococcal vaccines during outbreaks, and some countries, such as the UK, offer the MenB vaccine to lower the risk of gonorrhoea.

chemsex harm reduction

Chemsex, or party and play (PnP), means using drugs such as crystal meth, GHB/GBL, mephedrone or ketamine to have sex, often for long sessions or with groups. If you choose to use, these steps lower the risk. They don't make it safe.

Someone won't wake up, or is breathing slowly or strangely?

Call your local emergency number. If they're breathing, put them in the recovery position on their side and stay with them. If they're not breathing, the call handler will talk you through what to do. Tell responders what was taken. Some places, including most US states and Canada, have laws that protect people who call for help in an overdose from some drug charges. Whatever the law where you are, call: a life matters more.

If chemsex is taking more from you than it gives, specialist chemsex services and LGBTQ+ drug support exist in many cities, and they won't judge you. Find them on our support page.

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